Opthea Limited
OPT.ASXHealth Care
Opthea is a drug development company developing innovative, biologics-based therapies for the treatment of eye disease.
Market Data
$0.600
0.0%-$1.00
-100000.0x
$0.216
0.00%
-0.1%
Latest Earnings
Appendix 4D and Half Year Report for period 31 Dec 2025
2 March 2026
Opthea pivoted to a rare disease focus, completing a strategic review and terminating its Development Funding Agreement (DFA), resulting in a $339.9M profit swing. The $357.1M gain from DFA derecognition masked underlying operating losses of $7.1M as the company streamlined operations by 80% and repositioned to develop OPT-302 for Lymphangioleiomyomatosis (LAM), a rare lung disease, with $33.2M cash on hand and no near-term capital raise required. Key points: DFA settlement eliminates $377M liability, generating $357.1M accounting gain and resolving major balance sheet constraint; Strategic repositioning to LAM (rare lung disease) leverages existing OPT-302 asset with strong scientific rationale and unmet medical need; Dramatic cost reduction: 80% workforce cut, R&D expenses fell 99% to $1.3M; $10.8M R&D tax credit received in October 2025
Recent Announcements
Appendix 4D and Half Year Report for period 31 Dec 2025
Opthea pivoted to a rare disease focus, completing a strategic review and terminating its Development Funding Agreement (DFA), resulting in a $339.9M profit swing. The $357.1M gain from DFA derecognition masked underlying operating losses of $7.1M as the company streamlined operations by 80% and repositioned to develop OPT-302 for Lymphangioleiomyomatosis (LAM), a rare lung disease, with $33.2M cash on hand and no near-term capital raise required. Key points: DFA settlement eliminates $377M liability, generating $357.1M accounting gain and resolving major balance sheet constraint; Strategic repositioning to LAM (rare lung disease) leverages existing OPT-302 asset with strong scientific rationale and unmet medical need; Dramatic cost reduction: 80% workforce cut, R&D expenses fell 99% to $1.3M; $10.8M R&D tax credit received in October 2025
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