Entropy Neurodynamics Limited

ENP.ASX

Health Care

Research and development of pharmaceuticals and biotechnology

Market Data

Price

$0.032

+0.0%
Market Cap

$50.6M

P/E Ratio

-100000.0x

EPS

$-0.003

Div. Yield

0.00%

52-Week Change

-0.1%

Latest Earnings

Appendix 4D and Half Year Report for period 31 Dec 2025

27 February 2026

Revenue
$48.53
+999.2% YoY
NPAT
-$3.43
-14.8% YoY
EPS
$-0.00

Entropy Neurodynamics (formerly Tryptamine Therapeutics) reported a H1 2025 loss of $3.4M, down 14.8% year-on-year, with revenue up 999% to $48.5k from interest income. The company achieved major clinical milestones including first patient dosing in its world-first Binge Eating Disorder trial using TRP-8803, secured $6.1M in new funding and $2.6M in non-dilutive R&D loans, and signed a landmark biomarker collaboration with Imperial College London to develop an EEG-based precision psychiatry platform. Key points: First patient successfully dosed in world-first BED trial using TRP-8803 IV-infused psilocin in October 2025; second dose administered 15 December 2025 with full psychedelic response achieved; Two patients now enrolled in BED trial with strong initial interest and recruitment advancing; partnership with Butterfly Foundation supporting patient engagement; Landmark exclusive biomarker development agreement with Imperial College London (Professors Carhart-Harris and Mediano) to validate real-time EEG-based brain entropy biomarker for precision psychiatry and outcome prediction

Recent Announcements

27 Feb 2026 Actual Results Positive

Appendix 4D and Half Year Report for period 31 Dec 2025

Entropy Neurodynamics (formerly Tryptamine Therapeutics) reported a H1 2025 loss of $3.4M, down 14.8% year-on-year, with revenue up 999% to $48.5k from interest income. The company achieved major clinical milestones including first patient dosing in its world-first Binge Eating Disorder trial using TRP-8803, secured $6.1M in new funding and $2.6M in non-dilutive R&D loans, and signed a landmark biomarker collaboration with Imperial College London to develop an EEG-based precision psychiatry platform. Key points: First patient successfully dosed in world-first BED trial using TRP-8803 IV-infused psilocin in October 2025; second dose administered 15 December 2025 with full psychedelic response achieved; Two patients now enrolled in BED trial with strong initial interest and recruitment advancing; partnership with Butterfly Foundation supporting patient engagement; Landmark exclusive biomarker development agreement with Imperial College London (Professors Carhart-Harris and Mediano) to validate real-time EEG-based brain entropy biomarker for precision psychiatry and outcome prediction

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